Identification of biomarkers and therapeutic targets in inflammatory disease immunotherapy by high-dimensional single cell analysis and cluster proteomics (PRECISE)

This project aims at interoperability of the Swiss personalized health research infrastructure network by subjecting routinely acquired patient biopsies and clinical covariates across multiple centers to a central, standardized and integrated analysis workflow. This interoperability enabling pipeline will be made available for future studies by technology translation to dedicated facilities at ETHZ/UZH and by data exposition in the SPHN/SIB coordinated BioMedIT infrastructure. Our vision is to open this pipeline to all clinical centres nationally, as well as other disease classes and to implement routine procedures across Switzerland for sampling and biobanking.

Partners: ETHZ, University of Zurich, University Hospital of Basel

Applicant

Manfred Claassen

Type

Driver Project, jointly with SPHN

Health 2030 Institutions